Кислород. Молекула, изменившая мир

Nunomura, А., Реrrу, G., Pappolla, М. А., Friedland, R. Р., Hirai, К., Chiba, S. and Smith, М. А. Neuronal oxidative stress precedes amyloid-betа deposition in Down syndrome. Journal Neuropathology and Experimental Neurology 59: 1011 — 1017; 2000.

Вирус простого герпеса и болезнь Альцгеймера

Itzhaki, R. F., Lin, W. R., Shang, D., Wilcock, G. К, Faragher, В. аnd Jаmieson, G. А. Herpes simplex vims type 1 in brain and risk of Alzhеimеrʼs disease. Lancet 349: 241 — 244; 1997.

Воспаление и болезнь Альцгеймера

McGeer, Е. G. and McGeer, Р. L. The importance of inflammatory mechanisms in Alzheimerʼs disease. Experimental Gerontology 33: 371 — 378; 1998.

Smith, М. А., Rottkamp, С. А., Nunomura, А., Raina, А. К. and Perry, G. Oxidative stress in Alzheimerʼs disease. Biochimica et Biophysica Acta 1502: 139 — 144; 2000.

Mattson, М. Р. and Camandola, S. NFKB in neuronal plasticity and neurodegenerative disorders. Journal of Clinical Investigation 107: 247 — 254; 2001.

Табачный дым

Kodama, М., Kaneko, М., Aida, M., Inoue, F., Nakayama, Т. and Akimoto, Н. Free radical chemistry of cigarette smoke and its implication in human cancer. Anticancer Research 17: 433 — 437; 1997.

Lane, J. D., Opara, Е. С., Rose, J. Е. and Behm F. Quitting smoking raises whole blood glutathione. Physiology and Веhaviour 60: 1379 — 1381; 1996.

Диабет, гликирование и гены age

Brownlee, M. Negative consequences of glycation. Metabolism 49 (suppl.): 9 — 13; 2000.

Воспаление и атеросклероз

Becker, А. Е., de Boer, О. J. and van Der Wal А. С. The role of inflammation and infection in coronary artery disease. Annual Review of Меdicine 52: 289 — 297; 2001.

Окислительный стресс и воспаление при раке

Kovacic, P. and Jacintho, J. D. Mechanisms of carcinogenesis: focus on oxidative stress and electron transfer. Current Medical Chemistry 8: 773 — 796; 2001.

Меrсuriо, F. and Manning, А. М. NFKB as а primary regulator of the stress response. Oncogene 18: 6163 — 6171; 1999.

Глава 15. Устойчивость к малярии

Greenwood, В. М. Autoimmune disease and parasitic infections in Nigerians. Lancet ii: 380 — 382; 1968.

Clark, I. А., Al-Уаman, F. М., Cowden, W. В. and Rockett К. А.Does malarial tolerance, through nitric oxide, explain the low incidence of аutoimmunе disease in tropical Africa? Lancet 348: 1492 — 1494; 1996.

Enwere, G. C., Ota М. О. and Obaro S. К.The host response in malaria and depression of defence аgainst tuberculosis. Аппаls of Tropical Medicine and Parasitology 93: 669 — 678; 1999.

Болезнь Альцгеймера в Нигерии

Hendrie, Н. С., Ogunniyi, А., Hall, К. S., et al. Incidence of dementia and Alzheimer disease in two communities: Yoruba residing in Ibadan, Nigeria, and African Americans residing in Indianapolis, Indiana. Jоиrпаl оf the Атеriсап Medical Association 285: 739 — 747; 2001.

Farrer, L. А. Intercontinental epidemiology of Alzheimer disease. А global approach tо bad gene hunting. Jоиrпаl of thе Атеriсап Medical Association 285: 796 — 798; 2001.

Гемоксигеназа и подавление иммунитета

Taramelli, D., Recalcati, S., Basilico, N., Olliaro, Р. and Cairo, G. Macrophage preconditioning with synthetic malaria pigment reduces cytokine production via heme iron-dереndent oxidative stress. Laboratory Investigation 80: 1781 — 1788; 2000.

Soares, M. P., Lin, Y., Anrather, J., et al. Expression of home oxygenase-1 can determine cardiac xenograft survival. Nature Medicine 4: 1073 — 1077; 1998.

Motterlini, R., Foresti, R., Bassi, R. and Green, С. J. Curcumin, an antioxidant and аnti-inflammatorу agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress. Free Radical Biology and Medicine 28: 1303 — 1312; 2000.

Гигиеническая гипотеза

Rook, G. А. and Stanford, J. L. Give us this day our daily germs. Immunology Today 19: 113 — 116; 1998.

«Хрупкое здоровье» долгожителей

Yashin, А. I., De Benedictis, G., Vaupel, J. W., et al. Genes and longevity: lessons from studies of centenarians. Journal of Gеrопtology 55 А: В319 — В328; 2000.

Варианты митохондриальных генов и старение

Tanaka, M., Gong, J. S., Zhang, J., Yoneda, M. and Yagi, К. Mitochondrial genotype associated with longevity. Lancet 351: 185 — 186; 1998.