Мятежная клетка. Рак, эволюция и новая наука о жизни

Inukai, M., Toyooka, S., Ito, S. et al. (2006) Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non – small cell lung cancer, Cancer Research 66: 7854–7858 doi:10.1158/0008–5472. CAN-06–1951

Navin, N., Kendall, J., Troge, J. et al. (2011) Tumour evolution inferred by single-cell sequencing, Nature 472: 90–94 doi:10.1038/nature09807

Gerlinger, M., Rowan, A.J., Horswell, S. et al. (2012) Intratumor heterogeneity and branched evolution revealed by multiregion sequencing, N Engl J Med 366: 883–892 doi:10.1056/NEJMoa1113205

Darwin, C. R. (1881) The Formation of Vegetable Mould, Through the Action of Worms, John Murray, London, Chapter 1, p26

Lu, Y., Wajapeyee, N., Turker, M.S., and Glazer, P.M. (2014) Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1, Cell Reports 8: 501–513 doi:10.1016/j. celrep.2014.06.035

Ding, L., Ley, T., Larson, D. et al. (2012) Clonal evolution in relapsed acute myeloid leukemia revealed by whole genome sequencing, Nature 481: 506–510 doi:10.1038/nature10738

Hunter C., Smith, R., Cahill, D.P. et al. (2006) A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy, Cancer Res. 66: 3987–91 doi: 10.1158/0008–5472.CAN-06–0127

Russo, M., Crisafulli, G., Sogari, A. et al. (2019) Adaptive mutability of colorectal cancers in response to targeted therapies, Science 366: 1473–1480 doi:10.1126/science. aav4474

Keats, J.J., Chesi, M., Egan, J.B. et al. (2012) Clonal competition with alternating dominance in multiple myeloma, Blood 120: 1067–1076 doi:10.1182/blood-2012–01–405985

Morrissy, A. S., Garzia, L., Shih, D. J. et al. (2016) Divergent clonal selection dominates medulloblastoma at recurrence, Nature 529: 351–357 doi:10.1038/nature16478

Nowell, P.C. (1976) The clonal evolution of tumor cell populations, Science 194: 23–28 doi:10.1126/science.959840

Aktipis, C.A., Kwan, V.S.Y., Johnson, K.A. et al. (2011) Overlooking evolution: a systematic analysis of cancer relapse and therapeutic resistance research, PLoS ONE 6: e26100 doi:10.1371/journal.pone.0026100

Smith, M.P. and Harper, D.A.T. (2013) Causes of the Cambrian Explosion, Science 341: 1355–1356 doi:10.1126/ science.1239450

Notta, F., Chan-Seng-Yue, M., Lemire, M. et al. (2016) A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns, Nature 538: 378–382 doi:10.1038/nature19823

Chen, G., Bradford, W.D., Seidel, C.W. and Li, R. (2012) Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy, Nature 482: 246–250 doi:10.1038/nature10795

Potapova, T. A., Zhu, J. and Li, R. (2013). Aneuploidy and chromosomal instability: a vicious cycle driving cellular evolution and cancer genome chaos, Cancer Metastasis Reviews 32: 377–389 doi:10.1007/s10555–013–9436–6

Chen, G., Rubinstein, B. and Li, R. (2012). Whole chromosome aneuploidy: big mutations drive adaptation by phenotypic leap, BioEssays 34: 893–900 doi:10.1002/bies.201200069

Baker, D., Jeganathan, K., Cameron, J. et al. (2004) BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice, Nat Genet 36: 744–749 doi:10.1038/ng1382

Baker, D.J., Dawlaty, M.M., Wijshake, T. et al. (2013) Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan, Nature Cell Biology 15: 96–102 doi:10.1038/ncb2643

Sackton, K., Dimova, N., Zeng, X. et al. (2014) Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C, Nature 514: 646–649 doi:10.1038/nature13660

Martincorena, I. and Campbell, P.J. (2015) Somatic mutation in cancer and normal cells, Science 349: 1483–1489 doi:10.1126/science.aab4082

Stephens, P. J., Greenman, C. D., Fu, B. et al. (2011) Massive genomic rearrangement acquired in a single catastrophic event during cancer development, Cell 144: 27–40 doi:10.1016/j.cell.2010.11.055

Wu, S., Turner, K.M., Nguyen, N. et al. (2019) Circular ecDNA promotes accessible chromatin and high oncogene expression, Nature 575: 699–703 doi:10.1038/ s41586–019–1763–5

Garsed, D.W., Marshall, O.J., Corbin, V.D.A. et al. (2014) The architecture and evolution of cancer neochromosomes, Cancer Cell 26: 653–667 doi:10.1016/j.ccell.2014.09.010

Sheltzer, J.M., Ko, J.H., Replogle, J.M. et al. (2017) Single-chromosome gains commonly function as tumor suppressors, Cancer Cell 31: 240–255 doi:10.1016/j. ccell.2016.12.004

Relationship between incorrect chromosome number and cancer is reassessed after surprising experiments (2017). Cold Spring Harbor Laboratory website (published online 12 January 2017) bit.ly/2ZZwAXy