Мусорная ДНК. Путешествие в темную материю генома

9. Lee JT, Strauss WM, Dausman JA, Jaenisch R. A 450 kb transgene displays properties of the mammalian X-inactivation center. Cell. 1996 Jul 12;86(1):83-94.

10. Всеобъемлющее описание данного процесса см. в: Lee JT. The X as model for RNA’s niche in epigenomic regulation. Cold Spring Harb Perspect Biol. 2010 Sep; 2(9):a003749.

11. Xu N, Tsai CL, Lee JT. Transient homologous chromosome pairing marks the onset of X inactivation. Science. 2006 Feb 24:311(5764):1149-52.

12. Удивительные подробности распространения гемофилии среди царствующих домов Европы см. в: http://www.hemophilia.org/NHFWeb/MainPgs/MainNHF.aspx?menuid=178&contentid=6.

13. Подробности об этом заболевании см. в: http://www.nhs.uk/con-ditions/Rett-syndrome/Pages/lntroduction.aspx.

14. Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet. 1999 Oct; 23(2):185-8.

15. Подробности об этом заболевании см. в: http://www.nlm.nih.gov/medlineplus/ency/article/000705.htm.

16. Hoffman EP, Brown RH Jr, Kunkel LM. Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell. 1987 Dec 24;51(6):919-28.

17. Pena SD, Karpati G, Carpenter S, Fraser FC. The cllnicafconse^ quences of X'chromosome inactivation: Duchenne muscular dystrophy in one of monozygotic twins. J Neurol Scl. 1987 Jul; 79(3):337-44.

18. Shin T, Kraemer D, Pryor J, Liu L, Rugila J, Howe L, Buck S, Murphy K, Lyons L, Westhusin M. A cat cloned by nuclear transplantation. Nature. 2002 Feb 21;415(6874):859.

Глава 8

1. Schmitt AM, Chang H Y. Gene regulation: Long RNAs wire up cancer growth. Nature. 2013 Aug 29;500(7464):536-7.

2. Volders PJ, Helsens K, Wang X, Menten В, Martens L, Gevaert К, Vandesompele J, Mestdagh P. LNCipcdia: a database for annotated human long-noncoding RNA transcript sequences and structures. Nucleic Acids Res. 2013 Jan; 41(Database issue):D246-51.

3. ENCODE Project Consortium, Bernstein BE, Birney E, Dunham 1, Green ED, Gunter C, Snyder M. An integrated encyclopedia of DNA elements in the human genome. Nature. 2012 Sep 6;489(7414):57-74.

4. Tay Y, Rinn J, Pandolf PP. The multilayered complexity of ceRNA crosstalk and competition. Nature. 2014 Jan 16;505(7483):344-52.

5. Derrien T, Johnson R, Bussotti G, Tänzer A, Djebali S, Tilgner H, Guernec G, Martin D, Merkel A, Knowles DG, Lagarde J, Veeravalli L, Ruan X, Ruan Y, Lassmann T, Carninci P, Brown JB, Lipovich L, Gonzalez JM, Thomas M, Davis CA, Shiekhattar R, Gingeras TR, Hubbard TJ, Notredame C, Harrow J, Guigô R. The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res. 2012 Sep; 22(9): 1775-89.

6. Ulitsky I, Shkumatava A, Jan CH, Sive H, Bartel DP. Conserved function of HncRNAs in vertebrate embryonic development despite rapid sequence evolution. Cell. 2011 Dec 23;147(7): 1537-50.

7. Cabili MN, Trapnell C, Goff L, Koziol M, Tazon-Vega B, Regev A, Rinn JL. Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. Genes Dev. 2011 Sep 15;25( 18): 1915-27.

8. Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschieb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP. Mouse Genome Sequencing Consortium. Lineage-specific biology revealed by a finished genome assembly of the mouse. PLoS Biol. 2009 May 5;7(5):el000112.

9. Necsulea A, Soumillon M, Warnefors M, Liechti A, Daish T, Zeller U, Baker JC, Grützner F, Kaessmann H. The evolution of long non-coding RNA repertoires and expression patterns in tetrapods. Nature. 2014 Jan 30;505(7485):635-40.

10. Wahlestedt C. Targeting long non-coding RNA to therapeutically upregulate gene expression. Nat Rev Drug Dlscov. 2013 Jun; 12(6):433-46.

11. Mercer TR, Dinger ME, Sunkin SM, Mehler MF, Mattick JS. Specific expression of long noncoding RNAs in the mouse brain. Proc Natl Acad Sci USA. 2008 Jan 15;105(2):716-21.

12. Очень полезный обзор этого класса, объясняющий, какую роль он играет среди длинных некодирующих РНК, см. в: Ulitsky I, Bartel DP. lincRNAs: genomics, evolution, and mechanisms. Cell. 2013 Jul 3;154(1):26-46.