58. Parkinson’s Foundation announces new genetic initiative connecting Parkinson’s genetic data with clinical care [пресс-релиз]. Parkinson’s Foundation. March 6, 2018. https://parkinson.org/about-us/Press-Room/ Press-Releases/Parkinsons-Foundation-Announces-New-Genetic-Initiative-Connecting-Parkinsons-Genetic-Data-with-Clinical-Care. Accessed June 27, 2019.
59. Saunders-Pullman R, Mirelman A, Alcalay RN, et al. Progression in the LRRK2-associated Parkinson disease population.
60. CR, Jr. Passive immunization against poliomyelitis: the Hammon gamma globulin field trials, 1951–1953.
61. Там же.
62. Jankovic J, Goodman I, Safirstein B, et al. Safety and tolerability of multiple ascending doses of PRX002/RG7935, an anti-a-synuclein monoclonal antibody, in patients with Parkinson disease: a randomized clinical trial.
63. Fletcher K. Trials to treatments: vaccines for Parkinson’s. Medium. November 19, 2018. https://medium.com/parkinsons-uk/vaccines-for-parkinsons-b09634c84017. Accessed May 20, 2019.
64. Jankovic J, Goodman I, Safirstein B, et al. Safety and tolerability of multiple ascending doses of PRX002/RG7935, an anti-a-synuclein monoclonal antibody, in patients with Parkinson disease: a randomized clinical trial.
65. AFFiRiS AG. AFFiRiS announces top line results of first-in-human clinical study using AFFITOPE PD03A, confirming immunogenicity and safety profile in Parkinson’s disease patients. Cision PR Newswire. June 7, 2017. www.prnewswire.com/news-releases/affiris-announces-top-line-results-of-first-in-human-clinical-study-using-affitope-pd03a-confirming-immunogenicity-and-safety-profile-in-parkinsons-disease-patients-627025511.html. Accessed June 27, 2019; Affitope PD03A. Parkinsons’s News Today. https://parkinsonsnewstoday.com/ affitope-pd03a. Accessed March 29, 2019.
66. Kuhl MM. Vaccine for Parkinson’s reports positive results from boost study.
67. Dieleman JL, Baral R, Birger M, et al. US spending on personal health care and public health, 1996–2013.
68. Olanow CW, Rascol O, Hauser R, et al. A double-blind, delayed-start trial of rasagiline in Parkinson’s disease.
69. Olanow CW, Rascol O, Hauser R, et al. A double-blind, delayed-start trial of rasagiline in Parkinson’s disease.
70. Blandini F, Armentero MT, Fancellu R, Blaugrund E, Nappi G. Neuroprotective effect of rasagiline in a rodent model of Parkinson’s disease.
71. 45 million Americans forego medications due to costs, new analysis shows—9 times the rate of the UK [пресс-релиз]. Prescription Justice. February 6 2017. https://prescriptionjustice.org/ press_release/45-million-americans-forego-medications-due-to-costs-new-analysis-shows-9-times-the-rate-of-the-uk. Accessed June 27, 2019.
72. DiMasi JA, Grabowski HG, Hansen RW. Innovation in the pharmaceutical industry: new estimates of R&D costs.
73. Adams CP, Brantner VV. Estimating the cost of new drug development: is it really $802 million?