Танец жизни. Новая наука о том, как клетка становится человеком

[16] Piotrowska-Nitsche et al. Four-cell Stage Mouse Blastomeres, 479— 490; Morris et al. Developmental Plasticity Is Bound by Pluripotency, 756-765.

[17] Piotrowska-Nitsche, Zernicka-Goetz. Spatial Arrangement of Individual 4-Cell Stage Blastomeres, 487—500.

[18] Y. Kurotaki, K. Hatta, K. Nakao, Y. Nabeshima, T. Fujimori. Blastocyst Axis Is Specified Independently of Early Cell Lineage but Aligns with the ZP Shape. Science 316 (2007): 719—723. Doi: 10.1126/ science. 1138591.

[19] Richard L. Gardner. The Axis of Polarity of the Mouse Blastocyst Is Specified Before Blastulation and Independently of the Zona Pellucida. Human Reproduction 22. No. 3 (2007): 798—806. Doi: 10.1093/ humrep/del424.

[20] M. Bischoff, D.-E. Parfitt, M. Zernicka-Goetz. Formation of the Embryonic-Abembryonic Axis of the Mouse Blastocyst: Relationships Between Orientation of Early Cleavage Divisions and Pattern of Symmetric/Asymmetric Divisions. Development 135 (2008): 953—962. Doi:10.1242/dev.014316.

[21] M. E. Torres-Padilla, D. E. Parfitt, T. Kouzarides, M. Zernicka-Goetz. Histone Arginine Methylation Regulates Plan potency in the Early Mouse Embryo. Nature 445. No 7124 (2007): 214—218. Doi:10.1038/nature05458.

[22] Ibid.

[23] Fernando H. Biase, Xiaoyi Cao, Sheng Zhong. Cell Fate Inclination Within 2-Cell and 4-Cell Mouse Embryos Revealed by Single-Cell RNA Sequencing. Genome Research 24. No. 11 (2014): 1787—1796. Doi: 10.1101/gr. 177725.114; Junchao Shi, Qi Chen, Xin Li, Xiu-deng Zheng, Ying Zhang, Jie Qiao, Fuchou Tang, Yi Tao, Qi Zhou, Enkui Duan. Dynamic Transcriptional Symmetry-Breaking in Pre-implantation Mammalian Embryo Development Revealed by Single-Cell RNA-Seq. Development 142 (2015): 3468—3477. Doi:10.1242/ dev. 123950.

[24] Мубин Гулам, электронное письмо Роджеру Хайфилду, 17 сентября 2018 года; Мубин Гулам, интервью с Роджером Хайфилдом, 23 августа 2018 года.

[25] М. Goolam, A. Scialdone, S. J. L. Graham, I. С. Macaulay, A. Jedrusik, A. Hupalowska, Т. Voet, J. C. Marioni, M. Zernicka-Goetz. Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos. Cell 165 (2016): 61-74. Dor 10 1016/i cell.2016.01.047.

[26] A. Jedrusik, D.-E. Parfitt, G. Guo, M. Skamagki, J. B. Grabarek, M. H. Johnson, P. Robson, M. Zernicka-Goetz. Role ofCdx2and Cell Polarity in Cell Allocation and Specification of Trophectoderm and Inner Cell Mass in the Mouse Embryo. Genes and Development 22 (2008): 2692-2706. Doi: 10.1101 /gad.486108.

[27] Goolam et al. Heterogeneity in Oct4andSox2 Targets, 61-74.

[28] M D. White, J. F. Angiolini, Y. D. Alvarez, G. Kaur, Z. W. Zhao, E. Mocskos, L. Bruno, S. Bissiere, V. Levi, N. Plachta. Long-Lived Binding of Sox2 to DNA Predicts Cell Fate in the Four-Cell Mouse Embryo. Cell 165 (2016): 75-87. Doi: 10.1016/j.cell.2016.02.032.

[29] Ibid.

[30] S. A. Morris, Y. Guo, M. Zernicka-Goetz. Developmental Plasticity Is Bound by Pluripotency and the Fgfand Wnt Signaling Pathways. Cell Reports 2. No. 4 (2012): 756-765.

[31] N. Plachta, T. Bollenbach, S. Pease, S. E. Fraser, P. Pantazis. Oct4 Kinetics Predict Cell Lineage Patterning in the Early Mammalian Embryo. Nature Cell Biology 13 (2011): 117-123. Doi: 10.1038/ncb2154.

[32] White et al. Long-Lived Binding of Sox2 to DNA, 75-87.

[33] 1. Tabansky, A. Lenarcic, R. W. Draft, K. Loulier, D. B. Keskin, J. Rosains, J. Rivera-Feliciano, J. W. Lichtman, J. Livet, J. N. Stern, J. R. Sanes, K. Eggan. Developmental Bias in Cleavage-Stage Mouse Blastomeres. Current Biology 23 (2013): 21-31. Doi: 10.1016/j cub.2012.10.054.

[34] Ibid.

Глава 6. Вскрытие черного ящика

[1] J. W. Lichtman, S. E. Fraser. The Neuronal Naturalist: Watching Neurons in Their Native Habitat. Nature Neuroscience 4 (2001): 1215-1220. Doi:10.1038/nn754.

[2] Insoo Hyun, Amy Wilkerson, Josephine Johnston. Embryology Policy: Revisit the 14-Day Rule. Nature 533 (2016): 169-171. URL: www. nature.com/news/embryology-policy-revisitthe- 14-day-rule-1.19838.

[3] J. Carver, К. Martin, I. Spyropoulou, D. Barlow, I. Sargent, H. Mar-don. An In-Vitro Model for Stromal Invasion During Implantation of the Human Blastocyst. Human Reproduction 18 (2003): 283-290.

[4] William Richard Rice. The High Abortion Cost of Human Reproduction. bioRxiv (2018): 372193.

[5] A. T. Hertig, J. Rock, E. C. Adams. A Description of 34 Human Ova Within the First 17 Days of Development. American Journal of Anatomy 98. No. 31 (1956): 435-493. URL: https://doi.org/10.1002/ aja. 1000980306.

[6] Ibid.

[7] B. Fu, Y. Zhou, X. Ni, X. Tong, X. Xu, Z. Dong, R. Sun, Z. Tian, H. Wei. Natural Killer Cells Promote Fetal Development Through the Secretion of Growth-Promoting Factors. Immunity 47 (2017): 1100-1113. Doi: 10.1016/j.immuni.2017.11.018.