As he spoke, the man, puffing and blowing (при этих его словах незнакомец, тяжело и шумно дыша), rushed at our door and pulled at our bell (кинулся к нашей двери и /стал/ дергать колокольчик) until the whole house resounded with the clanging (пока весь дом не огласился звоном; clang — лязг, звон, бряцание, резкий металлический звук; to resound — громко звучать, раздаваться; оглашаться /with/).

A few moments later he was in our room (через минуту он уже был в нашей комнате), still puffing, still gesticulating (все еще тяжело дыша и жестикулируя), but with so fixed a look of grief and despair in his eyes (но в его глазах застыл такой горестный и отчаянный взгляд) that our smiles were turned in an instant to horror and pity (что наши улыбки тотчас превратились в тревогу и жалость = уступили место тревоге и жалости). For a while he could not get his words out (некоторое время он не мог вымолвить ни слова), but swayed his body and plucked at his hair like one (только раскачивался: «раскачивал свое тело» и дергал себя за волосы, как человек) who has been driven to the extreme limits of his reason (доведенный до пределов разума = до грани сумасшествия). Then, suddenly springing to his feet (вдруг он бросился вперед; to spring to one's feet — вскочить на ноги), he beat his head against the wall with such force (и ударился головой о стену с такой силой) that we both rushed upon him and tore him away to the centre of the room (что мы оба кинулись к нему и оттащили его на середину комнаты). Sherlock Holmes pushed him down into the easy-chair (Холмс усадил его в мягкое кресло) and, sitting beside him, patted his hand (и, сев рядом, похлопал его по руке) and chatted with him in the easy, soothing tones (и заговорил с ним так мягко, успокаивающе: «в тех легких/непринужденных, успокаивающих тонах»; to chat — непринужденно болтать, беседовать, разговаривать) which he knew so well how to employ (как он очень хорошо умел: «как он очень хорошо умел использовать»; to employ — употреблять, применять, использовать).

symptom ['sImpt@m], gesticulating [dZe'stIkjuleItIN], extreme [Ik'stri:m]

“Yes; I rather think he is coming to consult me professionally. I think that I recognize the symptoms. Ha! did I not tell you?”

As he spoke, the man, puffing and blowing, rushed at our door and pulled at our bell until the whole house resounded with the clanging.

A few moments later he was in our room, still puffing, still gesticulating, but with so fixed a look of grief and despair in his eyes that our smiles were turned in an instant to horror and pity. For a while he could not get his words out, but swayed his body and plucked at his hair like one who has been driven to the extreme limits of his reason. Then, suddenly springing to his feet, he beat his head against the wall with such force that we both rushed upon him and tore him away to the centre of the room. Sherlock Holmes pushed him down into the easy-chair and, sitting beside him, patted his hand and chatted with him in the easy, soothing tones which he knew so well how to employ.