Эгоистичная митохондрия. Как сохранить здоровье и отодвинуть старость

Munro D., et al. Low hydrogen peroxide production in mitochondria of the long-lived Arctica islandica: underlying mechanisms for slow aging. Aging Cell. 2013 Aug; 12(4):584–92. Epub 2013 May 6. doi:10.1111/acel.12082. Sinatra S. T. The Sinatra solution: metabolic cardiology. Laguna Beach, CA: Basic Health Publications, Inc; 2011.

Wallace D. C. Mitochondrial genetics: a paradigm for aging and degenerative diseases? Science. 1992 May 1; 256(5057):628–32. doi:10.1126/ science.1533953.

Wallace D. C. A mitochondrial bioenergetic etiology of disease. J Clin Invest. 2013 Apr; 123(4): 1405–12. Epub 2013 Apr 1. doi:10.1172/JCI61398.

Роль митохондрий в заболеваниях сердечно-сосудистой системы

Aon M. A. Mitochondrial dysfunction, alternans, and arrhythmias. Front Physiol. 2013 Apr 19; 4:83.

Buja L. M. The pathobiology of acute coronary syndromes: clinical implications and central role of the mitochondria. Tex Heart Inst J. 2013; 40(3):221–8.

Gorenkova N., et al. Conformational change of mitochondrial complex I increases ROS sensitivity during ischaemia. Antioxid Redox Signal. 2013 Oct; 19(13):1459–68. Epub 2013 Feb 18. doi:10.1089/ars.2012.4698.

Li H., Horke S., Förstermann U. Oxidative stress in vascular disease and its pharmacological prevention. Trends Pharmacol Sci. 2013 Jun; 34(6):313–9. Epub 2013 Apr 19. doi:10.1016/j.tips.2013.03.007.

Lonnrot K., et al. Control of arterial tone after long-term coenzyme Q10 supplementation in senescent rats. Brit J Pharmacol. 1998 Aug; 124(7):1500–6. doi:10.1038/sj.bjp.0701970.

Karamanlidis G., et al. Defective DNA replication impairs mitochondrial biogenesis in human failing hearts. Circ Res. 2010 May 14; 106(9):1541–8. doi:10.1161/CIRCRESAHA.109.212753.

Knight-Lozano C. A., et al. Cigarette smoke exposure and hypercholesterolemia increase mitochondrial damage in cardiovascular tissues. Circulation. 2002 Feb 19;105(7):849–54. doi:10.1161/hc0702.103977.

Madamanchi N. R., Runge M. S. Mitochondrial dysfunction in atherosclerosis. Circ Res. 2007 Mar 2;100(4):460–73.

Mercer J. R. Mitochondrial bioenergetics and therapeutic intervention in cardiovascular disease. Pharmacol Ther. 2014 Jan;141(1):13–20. Epub. doi:10.1016/j.pharmthera.2013.07.011.

Montaigne D, et al. Mitochondrial dysfunction as an arrhythmogenic substrate: a translational proof-of-concept study in patients with metabolic syndrome in whom post-operative atrial fibrillation develops. J Am Coll Cardiol. 2013 Oct 15; 62(16):1466–73. Epub 2013 May 1. doi:10.1016/j. jacc.2013.03.061.

Morales C. R., et al. Oxidative stress and autophagy in cardiovascular homeostasis. Antioxid Redox Signal. 2014 Jan 20; 20(3):507–518. Epub 2013 May 5. doi:10.1089/ars.2013.5359.

Nazarewicz R. R., Dikalov S. I. Mitochondrial ROS in the pro-hypertensive immune response. Am J Physiol Regul Integr Comp Physiol. 2013 May 8; 305:R98–100. Epub. doi:10.1152 /ajpregu.00208.2013.

Oeseburg H., et al. Bradykinin protects against oxidative stress-induced endothelial cell senescence. Hypertension. 2009 Feb; 53(Part 2):417–22. doi:10.1161/HYPERTENSIONAHA.108.123729.

Schleicher M., et al. Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence. J Cell Biol. 2008 Jan 14; 180(1):101–12. doi:10.1083/jcb.200706072.

Schriewer J. M., et al. ROS-mediated PARP activity undermines mitochondrial function after permeability transition pore opening during myocardial ischemia-reperfusion. J Am Heart Assoc. 2013 Apr 18; 2(2):e000159. doi:10.1161/JAHA.113.000159.

Stride N., et al. Impaired mitochondrial function in chronically ischemic human heart. Am J Physiol Heart Circ Physiol. 2013 Mar 29. Epub. doi:10.1152/ajpheart.00991.2012.

Wallace D. C. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet. 2005; 39:359–407. doi:10.1146 /annurev.genet.39.110304.095751. Yang Z., et al. Prenatal environmental tobacco smoke exposure promotes adult atherogenesis and mitochondrial damage in apoliprotein E-/— mice fed a chow diet. Circulation. 2004 Dec 14; 110(24):3715–20. doi:10.1161/01.CIR.0000149747.82157.01.

Yang Z., et al. The role of tobacco smoke induced mitochondrial damage in vascular dysfunction and atherosclerosis. Mutat Res. 2007 Aug 1; 621(1–2):61–74. doi:10.1016/j.mrfmmm.2007.02.010.

Феномен гладкой мускулатуры

Chitaley K., Weber D. S., Webb R. C. RhoA/Rho-kinase, vascular changes and hypertension. Curr Hypertension Rep. 2001; 3:139–144. doi:10.1007/ s11906-001-0028-4