Эгоистичная митохондрия. Как сохранить здоровье и отодвинуть старость

Esposito L. A., et al. Mitochondrial disease in mouse results in increased oxidative stress. Proc Natl Acad Sci U S A. 1999 Apr 27; 96(9):4820–5.

Fontaine E., Ichas F., Bernardi P. A ubiquinone-binding site regulates the mitochondrial permeability transition pore. J Biol Chem. 1998; 273:25734–40. Fontaine E., et al. Regulation of the permeability transition pore in skeletal muscle mitochondria. Modulation by electron flow through the respiratory chain complex i. J Biol Chem. 1998 May 15; 273(20):12662–8.

Geromel V., et al. The consequences of a mild respiratory chain deficiency on substrate competitive oxidation in human mitochondria. Biochem Biophys Res Comm. 1997 Aug; 236:643–6.

Karbowski M., et al. Free radical-induced megamitochondria formation and apoptosis. Free Radic Biol Med. 1999 Feb; 26(3–4):396–409. doi:10.1016/S0891-5849(98)00209-3.

Kopsidas G., et al. An age-associated correlation between cellular bioenergy decline and mtDNA rearrangements in human skeletal muscle. Mutat Res. 1998 Oct 12; 421(1):27–36.doi:10.1016/S0027-5107(98)00150-X.

Kovalenko S. A., et al. Tissue-specific distribution of multiple mitochondrial DNA rearrangements during human aging. Ann NY Acad Sci. 1998 Nov 20;854:171–81.

Ku H. H., Brunk U. T., Sohal R. S. Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species. Free Radic Biol Med. 1993 Dec; 15(6):621–7.

Lass A., Agarwal S., Sohal R. S. Mitochondrial ubiquinone homologues, superoxide radical generation, and longevity in different mammalian species. J Biol Chem. 1997 Aug 1; 272:19199–204. doi:10.1074/jbc.272.31.19199. Lass A., Sohal R. S. Comparisons of coenzyme Q bound to mitochondrial membrane proteins among different mammalian species. Free Radic Biol Med. 1999; 27(1–2):220–6.

Linnane A. W., et al. Mitochondrial DNA mutations as an important contributor to aging and degenerative diseases. Lancet. 1989 Mar 25;1(8639):642–5. doi:10.1016/S0140-6736(89)92145-4.

Linnane A. W., et al. The universality of bioenergetic disease and amelioration with redox therapy. Biochim Biophys Acta. 1995 May 24; 1271(1):191– 4. doi:10.1016/0925-4439(95)00027-2.

Linnane A. W., Kovalenko S., Gingold E. B. The universality of bioenergetic disease. Age-associated cellular bioenergetic degradation and amelioration therapy. Ann NY Acad Sci. 1998 Nov 20; 854:202–13. doi:10.1111/j.1749–6632.1998.tb09903.x.

Martinucci S., et al. Ca2+-reversible inhibition of the mitochondrial megachannel by ubiquinone analogues. FEBS Lett. 2000 Sep;480:89–94. doi:10.1016/S0014-5793(00)01911-6.

Michikawa Y., et al. Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication. Science. 1999 Oct 22; 286(5440):774–9. doi:10.1126 /science.286.5440.774.

Ozawa T. Genetic and functional changes in mitochondria associated with aging. Physiol Rev. 1997 Apr; 77(2):425–64.

Richter C., et al. Control of apoptosis by the cellular ATP level. 1996 Jan 8; FEBS Lett 378(2): 107–10. doi:10.1016/0014-5793(95)01431-4.

Rosenfeldt F. L., et al. Coenzyme Q10 in vitro normalizes impaired post-ischemic contractile recovery of aged human myocardium. Fifth China International Congress on TCVS; 2000 September; Beijing, China.

Rosenfeldt F. L., et al. Response of the human myocardium to hypoxia and ischemia declines with age: correlations with increased mitochondrial DNA deletions. Ann NY Acad Sci. 1998 Nov; 854:489–90. doi:10.1111/j.1749–6632.1998.tb09938.x.

Rowland M. A., et al. Coenzyme Q10 treatment improves the tolerance of the senescent myocardium to pacing stress in the rat. Cardiovasc Res. 1998 Oct; 40(1):165–73.

Sohal R. S., Sohal B. H., Orr W. C. Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies. Free Radic Biol Med. 1995 Oct; 19(4):499–504. doi:10.1016/0891-5849(95)00037-X.

Susin S. A., et al. Mitochondria as regulators of apoptosis: doubt no more. Biochim Biophys Acta. 1998 Aug 10; 1366(1–2):151–65. doi:10.1016/ S0005-2728(98)00110-8.

Turker M. S. Somatic cell mutations: can they provide a link between aging and cancer? Mech Aging Dev. 2000 Aug 15; 117(1–3):1–19. doi:10.1016/ S0047-6374(00)00133-0.

Wallace D. C. Mitochondrial diseases in man and mouse. Science. 1999 Mar 5; 283(5407): 1482–8. doi:10.1126/science.283.5407.1482.