Эгоистичная митохондрия. Как сохранить здоровье и отодвинуть старость

Zhang Y., Rosenberg P. A. The essential nutrient pyrroloquinoline quinone may act as a neuroprotectant by suppressing peroxynitrite formation. Eur J Neurosci. 2002 Sep; 16(6): 1015–24. doi:10.1046/j.1460–9568.2002.02169.x.

Zhu B. Q., et al. Pyrroloquinoline quinone (PQQ) decreases myocardial infarct size and improves cardiac function in rat models of ischemia and ischemia/reperfusion. Cardiovasc Drugs Ther. 2004 Nov; 18(6):421–31. doi:10.1007/s10557-004-6219-x.

Zhu B. Q., et al. Comparison of pyrroloquinoline quinone and/or metoprolol on myocardial infarct size and mitochondrial damage in a rat model of ischemia/reperfusion injury. J Cardiovasc Pharmacol Ther. 2006 Jun; 11(2):119–28. doi:10.1177/1074248406288757.

Темный шоколад

Al-Safi S. A., et al. Dark chocolate and blood pressure: a novel study from Jordan. Curr Drug Deliv. 2011 Nov; 8(6):595–9. doi:10.2174/156720111797635496.

Buitrago-Lopez A., et al. Chocolate consumption and cardiometabolic disorders: systematic review and meta-analysis. BMJ. 2011 Aug 26; 343:d4488. doi:10.1136/bmj.d4488.

Ellinger S., et al. Epicatechin ingested via cocoa products reduces blood pressure in humans: a nonlinear regression model with a Bayesian approach. Am J Clin Nutr. 2012 Jun;95(6): 1365–77. Epub 2012 May 2. doi:10.3945/ajcn.111.029330.

Golomb B. A., Koperski S., White H. L. Association between more frequent chocolate consumption and lower body mass index. Arch Intern Med. 2012 Mar 26; 172(6):519–21. doi:10.1001 /archinternmed.2011.2100.

Messerli F. H. Chocolate consumption, cognitive function, and Nobel laureates. N Engl J Med. 2012 Oct 18; 367(16):1562–4. Epub 2012 Oct 10. doi:10.1056/NEJMon1211064.

Nehlig A. The neuroprotective effects of cocoa flavanol and its influence on cognitive performance. Br J Clin Pharmacol. 2013 Mar; 75(3):716–27. doi:10.1111/j.1365–2125.2012.04378.x.

Nogueira L., et al. (-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle. J Physiol. 2011 Sep 15; 589(Pt 18):4615–31. Epub 2011 Jul 25. doi:10.1113/ jphysiol.2011.209924.

Persson I. A., et al. Effects of cocoa extract and dark chocolate on angiotensin-converting enzyme and nitric oxide in human endothelial cells and healthy volunteers — a nutrigenomics perspective. J Cardiovasc Pharmacol. 2011 Jan; 57(1):44–50. doi:10.1097/FJC.0b013 e3181fe62e3.

Sathyapalan T., et al. High cocoa polyphenol rich chocolate may reduce the burden of the symptoms in chronic fatigue syndrome. Nutr J. 2010 Nov 22; 9:55. doi:10.1186/1475-2891-9-55.

Кофермент Q10

Cooper J. M., et al. Coenzyme Q10 and vitamin E deficiency in Friedreich’s ataxia: predictor of efifcacy of vitamin E and coenzyme Q10 therapy. Eur J Neurol. 2008 Dec; 15(12):1371–9. doi:10.1111/j.1468–1331.2008.02318.x.

Crane F. L., Low H., Sun I. L. Evidence for a relation between plasma membrane coenzyme Q and autism. Front Biosci (Elite Ed). 2013 Jun 1; 5:1011–6.

Del Pozo-Cruz J., et al. Relationship between functional capacity and body mass index with plasma coenzyme Q10 and oxidative damage in community-dwelling elderly-people. Exp Gerontol. 2014 Apr; 52:46–54. Epub 2014 Feb 7.

Duberley K. E., et al. Effect of coenzyme Q10 supplementation on mitochondrial electron transport chain activity and mitochondrial oxidative stress in coenzyme Q10 deficient human neuronal cells. Int J Biochem Cell Biol. 2014 May; 50:60–3. Epub 2014 Feb 15. doi:10.1016/j. biocel.2014.02.003.

Liang J. M., et al. Role of mitochondrial function in the protective effects of ischaemic postconditioning on ischaemia/reperfusion cerebral damage. J Int Med Res. 2013 Jun 1; 41(3):618–27. Epub 2013 Apr 4. doi:10.1177/0300060513476587.

Langsjoen P. H., Langsjoen A. M. Supplemental ubiquinol in patients with advanced congestive heart failure. Biofactors. 2008; 32(1–4):119–28. doi:10.1002/biof.5520320114.

Lass A., Sohal R. S. Comparisons of coenzyme Q bound to mitochondrial membrane proteins among different mammalian species. Free Radic Biol Med. 1999 Jul; 27(1–2):220–6. doi:10.1016/S0891-5849(99)00085-4.

Mancuso M., et al. Coenzyme Q10 in neuromuscular and neurodegenerative disorders. Curr Drug Targets. 2010 Jan; 11(1):111–21. doi:10.2174/1 38945010790031018.

Matthews R. T., et al. Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc Natl Acad Sci U S A. 1998 Jul 21; 95(15):8892–7.