Почему тело дает сбой. Как ежедневные привычки могут незаметно нас убивать

астму, различные виды аллергии и аутоиммунных расстройств: Michael Elten et al., “Residential Greenspace in Childhood Reduces Risk of Pediatric Inflammatory Bowel Disease: A Population-Based Cohort Study”, American Journal of Gastroenterology 116, no. 2 (2021).

также и определяют его: Eileen Crist and Alfred I. Tauber, “Selfhood, Immunity, and the Biological Imagination: The Thought of Frank Macfarlane Burnet”, Biology and Philosophy 15 (1999); Alfred I. Tauber, “Moving Beyond the Immune Self?”, Seminars in Immunology 12 (2000).

расширил общепринятый взгляд: F. Macfarlane Burnet, Biological Aspects of Infectious Disease (Cambridge: Cambridge University Press, 1940); F. Macfarlane Burnet, The Virus as Organism (Cambridge: Cambridge University Press, 1946).

как утверждает философ Альфред Таубер, недостаточно: Tauber, “Moving Beyond the Immune Self?”.

Глава 16. Остров Пасхи

опубликовали работу: Michel Poulain et al., “Identification of a Geographic Area Characterized by Extreme Longevity in the Sardinia Island: The AKEA Study”, Experimental Gerontology 39, no. 9 (Sept. 1, 2004).

задался целью определить: Dan Buettner, email to author, May 2021.

Голодание позволяет замедлить старение: См., например: Rafael de Cabo and Mark P. Mattson, “Effects of Intermittent Fasting on Health, Aging, and Disease”, New England Journal of Medicine 381, no. 26 (Dec. 26, 2019); Elizabeth F. Sutton et al., “Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes”, Cell Metabolism 27, no. 6 (June 5, 2018); Michael J. Wilkinson et al., “Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with Metabolic Syndrome”, Cell Metabolism 31, no. 1 (2020); Adrienne R Barnosky et al., “Intermittent Fasting vs Daily Calorie Restriction for Type 2 Diabetes Prevention: A Review of Human Findings”, Translational Research: The Journal of Laboratory and Clinical Medicine 164, no. 4 (Oct. 2014).

начинают идти на спад: Chia-Wei Cheng et al., “Prolonged Fasting Reduces IGF1/PKA to Promote Hematopoietic-Stem-Cell-Based Regeneration and Reverse Immunosuppression”, Cell Stem Cell 14, no. 6 (June 5, 2014).

в том числе подавляя воспалительное поведение макрофагов: Stefan Jordan et al., “Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool”, Cell 178, no. 5 (2019).

на людях разных возрастных групп: Jeffrey A. Woods et al., “Exercise, Inflammation and Aging”, Aging and Disease 3, no. 1 (2012); Kaleen M. Lavin et al., “Effects of Aging and Lifelong Aerobic Exercise on Basal and Exercise-Induced Inflammation”, Journal of Applied Physiology 128, no. 1 (Jan. 2020).

подавляют хроническое низкоуровневое воспаление: См., например: Stoyan Dimitrov, Elaine Hulteng, and Suzi Hong, “Inflammation and Exercise: Inhibition of Monocytic Intracellular TNF Production by Acute Exercise Via β2-Adrenergic Activation”, Brain, Behavior, and Immunity 61 (March 1, 2017); Earl S. Ford, “Does Exercise Reduce Inflammation? Physical Activity and C-Reactive Protein among U. S. Adults”, Epidemiology 13, no. 5 (Sept. 2002); Peter T. Campbell et al., “A Yearlong Exercise Intervention Decreases CRP among Obese Postmenopausal Women”, Medicine & Science in Sports & Exercise 41, no. 8 (2009); Laura A Daray et al., “Endurance and Resistance Training Lowers C-Reactive Protein in Young, Healthy Females”, Applied Physiology, Nutrition, and Metabolism 36, no. 5 (Oct. 2011).

оказывают положительное влияние на большинство признаков: Nuria Garatachea et al., “Exercise Attenuates the Major Hallmarks of Aging”, Rejuvenation Research 18, no. 1 (Feb. 2015).

снижают количество макрофагов: Dannenberg and Berger, Obesity, Inflammation and Cancer.

модулируют поведение микроглии: Onanong Mee-inta, Zi-Wei Zhao, and Yu-Min Kuo, “Physical Exercise Inhibits Inflammation and Microglial Activation”, Cells 8, no. 7 (2019).

уменьшают количество воспалительного жира вокруг кровеносных сосудов: Mee-inta, Zhao, and Kuo, “Physical Exercise Inhibits Inflammation”.

провели эксперимент с «крысиной йогой»: Lisbeth Berrueta et al., “Stretching Impacts Inflammation Resolution in Connective Tissue”, Journal of Cellular Physiology 231, no. 7 (July 1, 2016).