15 McAleer C. W. et al. Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics
. Science Translational Medicine. 2019; 11: eaav1386; Edington C. D. et al. Interconnected microphysiological systems for quantitative biology and pharmacology studies. Sci. Rep. 2018; 8: 1–18.
Глава 9. Экосистема внутри вас
1 Sender R. et al. Revised estimates for the number of human and bacteria cells in the body.
PLOS Biology. 2016; 14: e1002533.2 Venter J. C. et al. Environmental genome shotgun sequencing of the Sargasso Sea.
Science. 2004; 304: 66–74.3 Schlomann B. H., Parthasarathy R. Timescales of gut microbiome dynamics
. Current Opinion in Microbiology. 2019; 50: 56–63.4 Durack J., Lynch S. V. The gut microbiome: Relationships with disease and opportunities for therapy.
Journal of Experimental Medicine. 2019; 216: 20–40; Douglas A. E. Fundamentals of Microbiome Science: How Microbes Shape Animal Biology. Princeton, NJ: Princeton University Press, 2018; The Gut Microbiome in Health and Disease / Haller D. (ed.). Cham, Switzerland: Springer, 2018; Tremlett H. et al. The gut microbiome in human neurological disease: A review. Ann. Neurol. 2017; 81: 369–382; Griffiths J. A., Mazmanian S. K. Emerging evidence linking the gut microbiome to neurologic disorders. Genome Medicine. 2018; 10: 98.5 Drew L. Microbiota: Reseeding the gut.
Nature. 2016; 540: S109 – S112; van Nood E. et al. Duodenal infusion of donor feces for recurrent clostridium difficile. New England Journal of Medicine. 2013; 368: 407–415; Colman R. J., Rubin D. T. Fecal microbiota transplantation as therapy for inflammatory bowel disease: A systematic review and meta-analysis. J. Crohns Colitis. 2014; 8: 1569–1581.6 Zmora N. et al. Personalized gut mucosal colonization resistance to empiric probiotics is associated with unique host and microbiome features
. Cell. 2018; 174: 1388–1405.e21.7 Round J. L., Mazmanian S. K. The gut microbiota shapes intestinal immune responses during health and disease.
Nat. Rev. Immunol. 2009; 9: 313–323; Hooper L. V. et al. Interactions between the microbiota and the immune system. Science. 2012; 336: 1268–1273; Jones T. A., Guillemin K. Racing to stay put: How resident microbiota stimulate intestinal epithelial cell proliferation. Curr. Pathobiol. Rep. 2018; 6: 23–28.8 Hill J. H. et al. A conserved bacterial protein induces pancreatic beta cell expansion during zebrafish development
. eLife. 2016; 5: e20145.9 Schwarzer M. et al. Lactobacillus plantarum strain maintains growth of infant mice during chronic undernutrition
. Science. 2016; 351: 854–857.10 Finucane M. M. et al. A taxonomic signature of obesity in the microbiome? Getting to the guts of the matter.
PLoS ONE. 2014; 9: e84689; Sze M. A., Schloss P. D. Looking for a signal in the noise: Revisiting obesity and the microbiome. mBio. 2016; 7: e01018– e01016.11 О заболеваемости холерой и ее лечении см. статьи на сайтах ВОЗ (https:
//www.who.int/news-room/fact-sheets/detail/cholera) и Центров по контролю и профилактике заболеваний США (https://www.cdc.gov/cholera/treatment/index.html).12 Russell B. et al. Type VI secretion system effectors: Poisons with a purpose
. Nat. Rev. Micro. 2014; 12: 137–148.