“Any machine is constructed somehow and does something,” Krivoshein was expounding. “The biological machine called Man also has these two parts to it: the basic one and the operative. The operative part — organs of sensation, the brain, motor nerves, and skeletal muscles — is for the most part subservient to man. The eyes, ears, the binding parts of the skin, the nerve endings in the nose and the tongue, and the pain and temperature receptors react to external stimulation, turn it into electrical impulses (just like the mechanism for information input in a computer), while the brain and the spinal column analyze and combine the impulses according to the 'stimulation — braking' principle (similar to the impulse cells of a machine). The synapses join and separate, sending commands to the skeletal muscles, which perform various actions — just like the executive mechanisms of a machine.
“Man controls the operative side of his organisms — he can even master reflexes, like pain, by will power. But with the basic side, which takes care of the fundamental process of life — metabolism — it isn't like that. That lungs suck in air; the heart forces blood into the dark crannies of the body; the gullet contracts and pushes pieces of food into the stomach; the pancreas secretes hormones and enzymes to reduce food to elements that the intestines can absorb; the liver excretes glucose into the blood. The thyroid and parathyroid produce wild things, thyroxin and parathyreodine, which determine whether a person will grow and mature or remain a cretinous dwarf, whether he will develop a sturdy skeletal system or whether his bones can be bent like pretzels. An inconsequential — looking growth by the base of the brain — the pituitary body — with the help of its secretions commands the entire mysterious kitchen of internal secretions as well as the functioning of the kidneys, blood pressure, and safe delivery in childbirth. And this part of the organism, which constructs man — his build, skull shape, psychology, health, and power — this part is not subject to the conscious mind!”
“Correct,” smiled Vano Aleksandrovich. “In your operative side I easily recognize the activity of the 'animal' or somatic nervous system and in the basic one, the realm of the 'vegetative' or sympathetic nervous system. These terms appeared in the eighteenth century; they used the Latin for animal and for plant. Personally, I don't think they're very apt. Perhaps your engineering terms will have greater success in the twentieth century. Well, continue, please.”
“Machines, even electronic ones, are constructed and made by man. Soon the machines will do it themselves; the principle is clear. But why can't man construct himself? Metabolism is subordinate to the central nervous system. The glands, blood vessels, and intestines are connected to the brain by the same kind of nerves as the muscles and sensory organs are. Why can't man control these processes the way he can wiggle his fingers? Why is man's conscious participation in this process limited to satisfying his appetite and thirst and several opposite needs? It's ridiculous. Homo sapiens, the king of nature, the crown of evolution, the creator of complex technology and art, is distinguished in the basic life process from cows and earthworms only in the use of knives and forks and alcohol!”
“Why is it so important to be able to bring sugar, enzymes, and hormones into the blood through will power?” Androsiashvili's bushy eyebrows arched. “Please be so kind as to tell me why, on top of all my worries in the department, I have to also think every hour about how much adrenaline and insulin I should produce in the pancreas and where I should direct it? The sympathetic system takes care of it for me, without bothering man — and that's fine!”
“Is it fine, Vano Aleksandrovich? What about disease?”
“Disease… so that's your angle: disease as an error in the workings of the basic construction system.” The professor's eyebrows turned into sinusoids. “The mistakes that we try to rectify with pills, compresses, vaccinations, and other operative interference, and usually without much success. But… disease is the result of those effects of the environment that the organism can't handle.”
“And why can't it? After all, we know in most cases what is harmful — that's the basis of disease prevention, epidemic control. We try, simply, to keep away from danger. But the environment keeps spewing out new mysteries: X — ray radiation, welding arcs, isotopes — “
“Enough!” The professor raised both hands in surrender. “I have the feeling that you have a secret answer on the tip of your tongue and you just can't wait for your interlocutor to bulge his eyes and ask with timid hope: 'But why? All right! Look: my eyes are open wide.” The whites of his eyes, shot with red, sparkled. “And I am asking the long — awaited question. Why can't people control their metabolism?”
“Because they've forgotten how it's done!” Krivoshein thundered.