He had divided the basement into two working areas. Most of the room was open, its floor and walls covered with double layers of clear, heavy plastic sheeting to keep out dirt and grime. Lab benches lined the walls, stacked with his precious equipment: a 1,000-power microscope, a gas spectrometer, fermenters to grow bacteria in solution. A freezer and refrigerator. Mouse cages and autoclaves and Bunsen burners and trays of slides and pipettes. In one corner he had installed a sealed safety cabinet connected through a filter into the house’s air vents. He kept goggles, gloves, gowns, and a portable respirator in a cabinet by the door, next to a small shower. Fluorescent lights overhead gave the room a bright institutional shine. The space was essentially a crude equivalent of a Biosafety Level 2 lab, like the one at McGill and every university in the world. BSL2 labs handle germs and viruses that are moderately dangerous and infectious, pathogens that might give their victims a bad fever but are unlikely to kill anyone. Ironically, plague can sometimes be handled in BSL-2 labs, because
But Tarik needed more than a BSL-2 lab for his experiments. He wasn’t just growing plague and anthrax; he wanted to aerosolize them, turn them into airborne particles that could be easily inhaled. For that he should have been working in a Biosafety Level 3 lab or, even better, a secure BSL-4 lab like the one at the Centers for Disease Control.
The standards for BSL-4 labs run hundreds of pages. They must have their own air supply, double air locks that cannot be opened simultaneously, and filters to scrub the air they exhaust. Scientists must never wear their lab clothes outside the lab. They must always shower before leaving, and the shower water itself must be chemically treated. Germs can be moved only after being put inside a double set of unbreakable containers. And for really tricky projects, scientists must work in a “suit area,” a special room where they wear a full body suit with its own oxygen supply, so they will never accidentally breathe the air around them.
Tarik understood the standards. He had seen photographs of victims of smallpox and plague, faces twisted in agony, bodies bloated in death. He respected the power of the vials in his refrigerator. And he would have preferred to run his experiments at the CDC. But that institution might have frowned on his work. So Tarik built his own suit area. He sealed a five-foot corner of the basement in floor-to-ceiling Plexiglas, then covered the Plexiglas with thick plastic sheeting, creating a plastic bubble whose air could not circulate into the rest of the room except through an intake and exhaust system protected by HEPA filters.
Inside the bubble Tarik needed his own sealed air supply. Because Canada, like other industrialized countries, restricts the sale of fullbody positive pressure suits, Tarik couldn’t order one. Instead he used a respirator and oxygen tanks like those worn by scuba divers. To avoid contaminating the open part of the basement, he installed a Plexiglas passage off the door to the bubble, creating a crude airlock. He always changed into and out of his respirator in the airlock. Inside the bubble he had installed a stand-alone safety cabinet that held a mouse cage and a nebulizer, a machine that blew air through liquids to produce aerosol sprays. On the bubble’s plastic floor he had placed a half-size refrigerator and a cage big enough for a cat or a small dog. He hadn’t used the cage yet, but he expected to change that soon.
The space wasn’t ideal. Tarik could work inside it for only short stretches, until his tanks ran out of oxygen. And his respirator wasn’t as reliable as a genuine BSL-4 pressure suit. Still, the bubble had worked so far. He hadn’t gotten sick, and neither had the mice in the open half of the basement, a crude but effective way to measure exposure. Too bad he couldn’t show his professors — they’d be impressed.
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ta r i k f l i c k e d o n the overhead lights and checked to be sure the benches and beakers and agar dishes were exactly as he had left them. Down here the street and the world seemed far away. Only the faint rustling of his mice intruded on the silence. He counted them, making sure none had gone missing.