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tarik wished khadri could see the basement now. He was certain his “uncle” would be impressed. Two days before, Tarik had moved colonies of Y. pestis from the agar dishes into beakers of brain-heart infusion broth. Now Tarik saw that the transfer had been successful. The broth inside the vials remained clear, but white rings of bacteria lined their glass walls — the sure sign of a plague colony. Unlike most germs, Y. pestis did not disperse readily in solution, preferring to remain clumped. Tarik poured the broth into a glass mixing dish, carefully scraping the colonies of Y. pestis off the walls of the beakers. Using a wire, he gently mixed the colonies until the bacteria were scattered through the broth. Now he would test aerosolizing the bacteria. He connected a simple rubber hose to a small electric pump. He dropped the free end of the hose into the dish and turned on the pump. A moment later bubbles began gurgling out of the broth, as if it were a primordial stew about to boil over. This was the most basic way to aerosolize bacteria, Tarik knew. But he wanted to see whether Y. pestis could survive being moved between the beakers and the dish, and whether this basic aerosol could cause infection. In the scientific vernacular, this was a proofof-concept experiment. And so Tarik had put six more mice in a cage beside the mixing dish. They crawled calmly around their metal pen, oblivious to their fate.

Tarik worked for another half hour inside the bubble, transferring plague colonies between agar dishes and beakers of broth. He had more experiments planned, and he would need much more Y. pestis. He took careful notes, recording the temperature and humidity in the cage, the number of bubbles rising from the dish every second. Simple stuff, to be sure. But most laypeople didn’t understand that a thousand hours of tedium in the lab paved the way for every breakthrough. One step at a time, and he would get where he needed to be.

9

the doorman tipped his cap as Exley walked into the Jefferson Hotel, her low heels clacking on the lobby’s marble floor, the hotel’s air conditioning a relief from the muggy summer night.

“Good evening, Ms. Exley.”

“How are you, Rafael?”

“Never better, ma’am.”

She turned right, into the lounge, a quiet red-walled room whose dark wood tables seemed as if they should be crowded with politicians and lobbyists. Instead the space was mostly empty. The Jefferson had never matched the glamour of the Hay-Adams, and with the arrival of the Ritz-Carlton and other five-star hotels it had fallen permanently into second-tier status, a dowager whose rooms filled after the rest sold out.

But Exley liked the hotel’s faded elegance, the bouquet of flowers in the lobby, the way the doormen knew her. Plus, the Jefferson was on Fifteenth Street, a short walk from her apartment. After a couple of drinks she could wobble home. Tonight she’d stopped in for a special treat, a meeting of the S.L. Club, five professional women who saw each other for drinks every few weeks. One was a reporter for the Post, another a lawyer at Williams & Connolly. They were all divorced or never married, all middle-aged or older. Exley hated to define herself as middle-aged. Ugh. But she was, by any reasonable standard. Soon enough she’d be closing in on menopause. Okay, maybe not that soon, but still.

The S.L. Club had no bylaws, no fees, and no real purpose, aside from giving its five members a chance to vent about work and family and sneak a couple of cigarettes that their kids didn’t need to see. Exley had met Lynette, its informal leader, at an interminable Fourth of July party three years before.

The five of them were friends, but not a part of one another’s lives. So they could be honest with each other about their sputtering parents and complicated children. About ex-husbands who had remarried and decided that they wouldn’t pay for private school for their kids anymore. About minor triumphs at work and home, bureaucratic victories or honors their kids had won. In fact, that was probably the best thing about the club. Women weren’t supposed to brag, and Exley liked having the chance to celebrate a little when things went right. She looked forward to these gatherings, even—

especially — when work became overwhelming, as it had been for months. But tonight she was distracted.

they were in the corner, as usual, and she was late, as usual. She took the last seat, a glass of wine already poured for her. “To the Sophisticated Ladies,” they all said, glasses raised.

“The Sophisticated Ladies.” Clink.

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