В поисках памяти: Возникновение новой науки о человеческой психике

Прекрасный обзор долговременной потенциации можно найти в книге: T. Bliss, G. Collingridge & R. Morris, eds., LTP: Long-Term Potentiation (Oxford: Oxford University Press, 2003). В этом сборнике опубликовано немало полезных статей, в частности следующие: P. Andersen, A prelude to long-term potentiation; R. Malinow, AMPA receptor trafficking and long-term potentiation; R. G. M. Morris, Long-term potentiation and memory; R. A. Nicoll, Expression mechanisms underlying long-term potentiation: a postsynaptic view.

Другие сведения, приведенные в этой главе, почерпнуты из следующих источников:

Baudry, M., R. Siman, E. K. Smith & G. Lynch. Regulation by calcium ions of glutamate receptor binding in hippocampal slices. Euro. J. Pharmacol. 90, no. 2–3 (1983): 161–168.

Bliss, T. V. & T. Lamo. Long-lasting potentiation of synaptic transmission in the dentate gyrus of the anesthethized rabbit following stimulation of the perforant path. J. Physiol. 232 (1973): 331–356.

Collingridge, G. L., S. J. Kehl & H. McLennan. Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus. J. Physiol. (London) 334 (1983): 33–46.

Curtis, D. R., J. W. Phillis & J. C. Watkins. The chemical excitation of spinal neurons by certain acidic amino acids. J. Physiol. 150 (1960): 656–682.

Eccles J. C. The Physiology of Synapses. Berlin: Springer Verlag, 1964.

Hebb, D. O. The Organization of Behavior: A Neuropsychological Theory. New York: Wiley, 1949; приведенная цитата – стр. 62.

Nowak, L., P. Bregestovski, P. Ascher, A. Herbet & A. Prochiantz. Magnesium gates glutamate-activated channels in mouse central neurons. Nature 307 (1984): 462–465.

O’Dell, T. J., S. G. N. Grant, K. Karl, P. M. Soriano & E. R. Kandel. Pharmacological and genetic approaches to the analysis of tyrosine kinase function in long-term potentiation. Cold Spring Harbor Symp. Quant. Biol. 57 (1992): 517–526.

Roberts, P. J. & J. C. Watkins. Structural requirements for inhibition for L-glutamate uptake by glia and nerve endings. Brain Res. 85, no. 1 (1975): 120–125.

Schacter, D. L. Searching for Memory: The Brain, the Mind and the Past. New York: Basic Books, 1996.

Spencer, W. A. & E. R. Kandel. Electrophysiology of hippocampal neurons. IV: Fast prepotentials. J. Neurophysiol. 24 (1961): 272–285.

Westbrook, G. L. & M. L. Mayer. Glutamate currents in mammalian spinal neurons resolution of a paradox. Brain Res. 301, no. 2 (1984): 375–379.

21. Синапсы хранят и наши самые теплые воспоминания

Методы получения генетически модифицированных мышей описаны в статьях: R. L. Brinster & R. D. Palmiter. Induction of foreign genes in animals. Trends Biochem. Sri. 7 (1982): 438–440 и M. R. Capecchi, High-efficiency transformation by direct microinjection of DNA into cultured mammalian cells. Cell 22, no. 2 (1980): 479–488.

Первые данные об эффекте нокаута генов на долговременную потенциацию и пространственную память были опубликованы в статьях: S. G. N. Grant, T. J. O’Dell, K. A. Karl, P. L. Stein, P. Soriano & E. R. Kandel, Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice. Science 258 (1992): 1903–1910; A. J. Silva, R. Paylor, J. M. Wehner & S. Tonegawa, Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice. Science 257 (1992): 206–211.