Эпигенетика

Chen CM., ChenH.L., HsiauT.H., HsiauA.H., ShiH,, Brock G.J., Wei S.H., Caldwell C.W., Yan P.S., and Huang T.H., 2003. Methylation target array for rapid analysis of CpG island hypermethyla-tion in multiple tissue genomes. Am. J. Pathol. 163: 37-45.

Chen W., Cooper T.K., Zahnow C.A., Overholtzer M., Zhao Z., Ladanyi M., Karp J.E., Gokgoz N., Wunder J.S., Andrulis I.L., et al., 2004. Epigenetic and genetic loss of Hid function accentuates the role ofp53 in tumorigenesis. Cancer Cell 6: 387—398.

Chen W.Y, Wang D.H., Yen R.C., Luo J., Gu W, and Baylin S.B., 2005. Tumor suppressor HIC1 directly regulates S1RT1 to modulate p53-dependent DNA-damage responses. Cell 123: 437-448.

Chen W.Y., Zeng X., Carter M.G.. Morrell C.N.. Chiu Yen R.W., Esteller M., Watkins D.N., Herman J.G., Mankowski J.L., and Baylin S.B., 2003. Heterozygous disruption of Hie /predisposes mice to a gender-dependent spectrum of malignant tumors. Nat. Genet. 33: 197-202.

Dammann R., Li C., Yoon J.H., Chin P.L., Bates S., and Pfeifer G.P., 2000. Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. Nat. Genet. 25: 315-319.

Daskalakis M., Nguyen T.T., Nguyen C., Guldbeig P., Kohler G., Wijermans P., Jones P.A., and Lubbert M., 2002. Demethylation of a hypermethylated P15/INK4B gene in patients with my-elodysplastic syndrome by 5-Aza-2’-deoxycytidine (decitabine) treatment. Blood 100: 2957-2964.

Di Croce L., Raker V.A., Corsaro M., Fazi E, Fanelli M., Faretta M., Fuks E, Lo Coco E, Kouzarides T., Nervi C., et al., 2002. Methyl-transferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science 295: 1079-1082.

Egger G., Liang G., Aparicio A., and Jones P.A., 2004. Epigenetics in human disease and prospects for epigenetic therapy. Nature 429: 457-463.

Ehrlich M., Gama-Sosa M.A., Huang L.H., Midgett R.M., Kuo K.C., McCune R.A., and Gehrke C., 1982. Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells. Nucleic Acids Res. 10: 2709-2721.

Esteller M., Risques R.A., Toyota M., Capella G., Moreno V., Peinado M.A., Baylin S.B., and Herman J.G., 2001a. Promoter hypermethylation of the DNA repair gene 0(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumori-genesis. Cancer Res. 61: 4689-4692.

EstellerM., Fraga M.F., Guo M., Garcia-Foncillas J., HedenfalkL, Godwin A.K., Trojan J., Vaurs-Barriere C., Bignon Y.J., Ramus S., et al., 2001b. DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis. Hum. Mol. Genet. 10: 3001-3007.

Fahmer J.A., Eguchi S., Herman J.G., and Baylin S.B., 2002. Dependence of histone modifications and gene expression on DNA hypermethylation in cancer. Cancer Res. 62: 7213-7218.

Feinberg A.P. and Vogelstein B., 1983. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 301: 89-92.

Feinberg A.P., Gehrke C.W., Kuo K.C., and Ehrlich M., 1988. Reduced genomic 5-methylcytosine content in human colonic neoplasia. Cancer Res. 48: 1159-1161.

Finch P.W., He X.. Kelley M.J., Uren A.. Schaudies R.P., Popescu N.C., Rudikoff S., Aaronson S.A., Varmus H.E., and Rubin J.S., 1997. Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action. Proc. Natl. Acad. Sci. 94: 6770-6775.

Flatau E., Bogenmann E., and Jones P.A., 1983. Variable 5-methylcy-tosine levels in human tumor cell lines and fresh pediatric tumor explants. Cancer Res. 43: 4901-4905.

Frost P., Liteplo R.G., Donaghue T.P., and Kerbel R.S., 1984. Selection of strongly immunogenic “turn” variants from tumors at high frequency using 5-azacytidine. J. Exp. Med. 159: 1491-1501.

Fuks E., Hurd P.J., Deplus R., and Kouzarides T., 2003. The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase. Nucleic Acids Res. 31: 2305-2312.

Fuks E., Burgers W.A., Godin N., Kasai M., and KouzaridesT., 2001. Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription. EMBO J., 20: 2536-2544.

Gaudet E., Hodgson J.G., Eden A., Jackson-Grusby L., Dausman J., GrayJ.W, Leonhardt H., and Jaenisch R., 2003. Induction of tumors in mice by genomic hypomethylation. Science 300: 489-492.

Gazzoli I., Loda M., Garber J., Syngal S., and Kolodner R.D., 2002. A hereditary nonpolyposis colorectal carcinoma case associated with hypermethylation of the MLH1 gene in normal tissue and loss of heterozygosity of the unmethylated allele in the resulting microsatellite instability-high tumor. Cancer Res. 62: 3925-3928.