“common factor of reducing…”: Mann 1974. “instant money nutritionists”: Stare 1987:xxx. “very lucrative…”: Whelan and Stare 1983:26.
The Harvard nutrition department’s $5 million building, and the “lead gift”: Stare 1987:xv–xvi. Stare as the defender of sugar and additives: Rosenthal et al. 1976.
Hill’s articles in
Hill received $300,000 from NIH: NIH Extramural Awards by State and Foreign Site: http://grants1.nih.gov/grants/award/state/state.htm. $5 million: e-mail from Marguerite Klein, NIH program officer for the Atkins diet trial.
“A resolution…”: Novin 1978:31.
CHAPTER TWENTY-FOUR:
THE CARBOHYDRATE HYPOTHESIS, III: HUNGER AND SATIETY
Sidbury described: Sidbury and Schwartz 1975 (“rational basis” “minimum of anguish…,” 66). His three-page article: Schwartz and Sidbury 1974. Sidbury noted: Sidbury and Schwartz 1975:66–67. Sidbury’s diet: Ibid.:67–69.
Dietary fat prolongs drainage of nutrients: Davidson and Passmore 1963:97.
Mayer’s glucostat hypothesis: Mayer 1968:20–24.
lipostatic regulation: Kennedy 1961. Set point: See Keesey 1980.
“weight loss triggers…”: Stunkard 1980:9. “It is not appealing…”: Quoted in Rovner 1986. Mysterious mechanism: Davis and Wirtshafter 1978.
The more fundamental criticism: This idea, and that of the settling point, are in ibid.
“black hole”: Interview, Donald Novin.
“In human beings and animals…”: Richter 1976:224.
Experimental observations on hunger, thirst, and palatability: Ibid. (“As a result…,” 198).430 “Rats will make every…”: Ibid.:210. “Food acceptance and the urge…”: Adolph 1947:122.
“phenomenal…”: Bellisle et al. 2003. “incredibly brilliant”: Interview, Stephen Woods. Le Magnen’s life and career: Le Magnen 2001.
Rats ate discrete meals: See Le Magnen 1976. See also Le Magnen 1971, his seminal paper on the physiological psychology of hunger.
Two fundamental observations: Le Magnen 1971:213–19. “quantitative deficiencies…”: Adolph 1947:122.
“All increase or decrease…”: Le Magnen 1971:220.
While they’re sleeping: Ibid.
“The restitution…”: Ibid.:238. “spare”: Ibid.:243.
“indirect and passive consequences…”: Le Magnen 1981:315.
Insulin is the driver: Le Magnen 1976:99–100.
Several variations of the hypothesis: Le Magnen 1984; Toates and Booth 1974; Friedman and Stricker 1976.
Three propositions: Friedman and Stricker 1976 (“adequate for them…,” 413).
The simplest possible explanation: Ibid. (“Hunger appears,” 424). “The primitive goal”: Hoebel and Hernandez 1993:43.
We’re not much more complicated than insects: Hoebel and Hernandez 1993; Lepkovsky 1973. “feeding behavior removes…”: Stricker 1978.
“Energy metabolism”: Friedman and Stricker 1976:413.
“harmony of tissue metabolisms”: Ibid.:413.
What the body regulates: Le Magnen 1984.
Le Magnen demonstrated this: Le Magnen 1981.
“It is not a paradox…”: Le Magnen 1984:517.
Food availability most important to fertility: Bronson 1988:88. Body fat, as commonly believed: Frisch and McArthur 1974. Availability of metabolic fuels: Schneider and Wade 1989 and Wade and Schneider 1992.
Wade and Schneider explained: Wade and Schneider 1992:246–47.
Nicotine as weight-loss drug: Filozof et al. 2004.
Excess calories not enough to explain weight gain: Perkins 1993. Rodin reported: Rodin 1987. Physical activity: Perkins 1993.
Nicotine and LPL: Chajek-Shaul et al. 1990; Perkins 1993; Sztalryd et al. 1996; Carney and Goldberg 1984. Fenfluramine and LPL: Deshaies et al. 1994.
The adjustable regulator: See Mrosovsky 1985:45–46.
Woods and Porte observed: Woods and Porte 1976:274. Seasonal weight variations in hibernators: Le Magnen 1988: Florant et al. 1985.
Seasonal variations in insulin levels: Fahlen et al. 1971; Behall et al. 1984. In LPL activity: Donahoo et al. 2000. Spring and fall weight changes: See, for instance, Andersson and Rossner 1992.
“arises mainly from human…”: Ramirez et al. 1989.
Le Magnen first noted: See Le Magnen 2001. “It is often said…”: Pavlov 1955:109.
Rats given the choice: Le Magnen 1978. For similar experiments done by Anthony Sclafani, see Sclafani and Nissenbaum 1988.
“In evolution…”: Quoted in Goleman 1989.
First wave of insulin secretion: Simpson et al. 1968. “The pancreas has no idea…”: Interview, Gerold Grodsky.
“the metabolic background…”: Le Magnen 1985:59. “In man…”: Le Magnen 1978.